ea0070aep391 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020
Aghajanova Elena
, Melkonyan Arthur
, Alchujyan Nina
, Gayane Bayburdyan
, Hovhannisyan Margarita
, Navasardyan Lusine
, Markosyan Renata
, Kalantaryan Lusine
, Issa Vrej
, Arakelyan Lusine
, Gevorgyan Zara
Introduction: Incidence of type 1 diabetes mellitus (T1DM) is rising steadily around the globe, including Armenia. It is one of the most common autoimmune and metabolic disorders in pediatric population, resulting from autoimmune destruction of pancreatic β-cells leading to insulin deficiency. Gut microbiota (GM) is reportedly involved in the pathogenesis of T1DM likely by influencing the immune response with the help of arginine-metabolizing enzymes. Arginase i...